PRODUCT DETAILS

About Desrem Injection

REMDESIVIR belongs to a group of anti-viral medicines called SARS-CoV-2 nucleotide analogue RNA polymerase inhibitor used to treat coronavirus disease requiring hospitalisation. Coronavirus disease, also known as SARS-CoV-2 (Severe Acute Respiratory Syndrome Corona Virus 2), is an infectious disease caused by the corona virus.
 
REMDESIVIR contains ‘Remdesivir, which binds to the viral-RNA dependant RNA polymerase enzyme, an enzyme that helps the coronavirus to replicate itself. This inhibits viral replication by premature termination of RNA transcription. Thereby, REMDESIVIR lowers virus load in the body and helps treat the infection.
 

Uses of Desrem Injection

Coronavirus disease (COVID 19).

Medicinal Benefits of Desrem Injection

REMDESIVIR belongs to a group of anti-viral medicines called SARS-CoV-2 nucleotide analogue RNA polymerase inhibitor. REMDESIVIR is used to treat corona virus disease requiring hospitalisation. REMDESIVIR binds to the viral-RNA dependant RNA polymerase enzyme, an enzyme that helps the corona virus to replicate itself. This inhibits viral replication by premature termination of RNA transcription. Thereby, REMDESIVIR lowers virus load in the body and helps treat the infection.

Directions for Use

REMDESIVIR should be administered by a healthcare professional; do not self-administer. REMDESIVIR should be administered only in a hospital or a healthcare setting capable of providing in-patient hospital care. Depending on your medical condition, your doctor will decide for how long you need to take REMDESIVIR.

Side Effects of Desrem Injection

• Nausea
• Increased transaminase levels
• Increased prothrombin time

Similar Drugs

For informational purposes only. Consult a doctor before taking any medicines.

In-Depth Precautions and Warning

Drug Warnings

Do not take REMDESIVIR if you are allergic to any of its contents. Inform your doctor if you have heart, liver or kidney problems. Consult your doctor before taking REMDESIVIR if you are pregnant, think you are pregnant or breastfeeding. REMDESIVIR is indicated for use only in patients above 12years, weighing at least 40kg. The safety of and effectiveness of REMDESIVIR in children below 12years is unknown. Transaminase levels should be monitored before and during the treatment with REMDESIVIR. Treatment with REMDESIVIR should be discontinued if the ALT (Alanine aminotransferase) levels are greater than ten times the upper limit of normal. Keep your doctor informed about your health condition and the medicines you are taking to prevent any side effects/interactions.

Drug Interactions

Drug-Drug Interaction:

REMDESIVIR may have interaction with antimalarials (chloroquine, hydroxychloroquine)

Drug-Disease Interaction:

REMDESIVIR may have interactions in patients with increased risk of transaminase elevations and infusion-related reactions.

Safety Advice

ALCOHOL

It is not known whether REMDESIVIR interacts with alcohol. Please consult your doctor.

PREGNANCY

There is insufficient data regarding the safety of REMDESIVIR during pregnancy. Please consult a doctor before taking REMDESIVIR if you are pregnant or think you might be pregnant.

BREAST FEEDING

There is insufficient data regarding the passage of REMDESIVIR into breastmilk. Please consult a doctor before taking REMDESIVIR if you are breastfeeding.

DRIVING

It is unknown if REMDESIVIR affects driving. Drive or operating machinery only if you are alert.

LIVER

The effectiveness of REMDESIVIR in patients with liver impairment have not been evaluated. Please consult your doctor before taking REMDESIVIR if you have a liver impairment or any concerns regarding this.

KIDNEY

The effectiveness of REMDESIVIR in patients with kidney impairment have not been evaluated. Please consult your doctor before taking REMDESIVIR if you have kidney impairment or any concerns regarding this.